| Set | Genes |
|---|---|
| NP × UC program | 551 (473 up, 78 down) |
| NP × CD program | 226 (174 up, 52 down) |
| Core (both diseases) | 187 |
| Union (matrix rows) | 590 |
| Evidence layers per gene | 1 layer: 28 · 2 layers: 315 · 3 layers: 217 · 4 layers: 30 |
| Validation cohorts | NP: GSE338426 (14v8), GSE198950, GSE267331 (dupilumab 47 pairs / placebo 19 pairs); gut: GSE75214 (n=194), GSE193677 (n=2,490, program-level); sc: GSE235711 (20 donors), GSE116222; spatial: GSE235714 (40 ROIs); protein: PXD050335 |